Impact of proximal muscle weakness of lower limbs on balance and functionality of individuals with Charcot-Marie-Tooth type 2 disease

Introduction: Charcot-Marie-Tooth disease (CMT) is the most prevalent genetically determined neurological condition in the world, individuals have muscle weakness, atrophy and sensory deficit. Objective: Assess lower limb and trunk muscle strength in individuals with CMT type 2 and its correlations...

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Detalles Bibliográficos
Autores: Vasconcelos , Juliana Moreira de Alcantara e, Silva, Jessica Paloma Rosa, Oliveira, Paulo Marcio Pereira, Neves, Eduardo Luis de Aquino, Coelho de Souza, Cyntia, Barreto, Lidiane Carine Lima Santos, Cajueiro, Catarina Andrade Garcez, Costa, Iandra Maria Pinheiro de França, Araujo, Adriano Antunes de Souza, Nunes, Paula Santos
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Brasil
Institución:Universidade Federal de Itajubá (UNIFEI)
Repositorio:Research, Society and Development
Idioma:portugués
OAI Identifier:oai:ojs.pkp.sfu.ca:article/33108
Acceso en línea:https://rsdjournal.org/index.php/rsd/article/view/33108
Access Level:acceso abierto
Palabra clave:Charcot-Marie-Tooth
Força Muscular
Equilíbrio postural
Funcionalidade.
Fuerza muscular
Equilibrio postural
Funcionalidad.
Muscle strength
Postural balance
Functionality.
Descripción
Sumario:Introduction: Charcot-Marie-Tooth disease (CMT) is the most prevalent genetically determined neurological condition in the world, individuals have muscle weakness, atrophy and sensory deficit. Objective: Assess lower limb and trunk muscle strength in individuals with CMT type 2 and its correlations with balance and functionality. Methods: Cross-sectional study, with a sample of fifteen individuals in the CMT2 group (CMT2G) and fifteen in the control group (CG). To assess muscle strong (MS), the dynamometer was used; balance through stabilometry (Velocity of the Center of Pressure Oscillation (VCPo) anteroposterior (AP) and latero-lateral (LL); and the Berg Balance Scale (BSE); and for functional performance, the Time Up and Go (TUG). Results: There was a significant reduction in proximal MS of lower limbs, abdominal and paravertebral; lower BSE score and lower TUG of CMT2G compared to CG. When analyzing the correlations of LL and trunk strength with VCPoAP in CMT2G (individuals with a mild score), the muscles with the highest correlation were: hip and paravertebral extensors/abductors/adductors, while in moderate/severe individuals, there was a regular correlation with hip and paravertebral flexors. In the correlations with BSE (light score), the paravertebral muscles had a regular correlation and in the most affected there was a strong correlation with the hip extensors/flexors/abductors and regular with the abdominals. In the correlations with the TUG (light score), there was a regular correlation with the hip, abdominal and paravertebral flexors. In moderate/severe individuals, the hip and paravertebral flexors had a slight correlation.