Uso de cetoanálogos para redução da amonemia em ratos submetidos a exercícios físicos

Concentration of ammonia in blood increases during endurance exercise and can be toxic for muscle cells and brain metabolism, potentially leading to both peripheral and central fatigue. Intense exercise can promote failure in replace ATP leading to greater deamination of AMP and consequent increase...

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Detalles Bibliográficos
Autor: Almeida, Rosemeire Dantas de
Tipo de recurso: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Institución:Universidade Federal de Uberlândia (UFU)
Repositorio:Repositório Institucional da UFU
Idioma:portugués
OAI Identifier:oai:repositorio.ufu.br:123456789/15718
Acceso en línea:https://repositorio.ufu.br/handle/123456789/15718
Access Level:acceso abierto
Palabra clave:Cetoácidos
Exercícios físicos - Aspectos fisiológicos
Amônia
Exercício
Ammonia
Exercise
Ketoacids
CNPQ::CIENCIAS BIOLOGICAS::GENETICA
Descripción
Sumario:Concentration of ammonia in blood increases during endurance exercise and can be toxic for muscle cells and brain metabolism, potentially leading to both peripheral and central fatigue. Intense exercise can promote failure in replace ATP leading to greater deamination of AMP and consequent increase in blood ammonia. High concentration of ammonia is toxic and harms the performance. Keto acids has been proposed to capture the blood nitrogen compounds. Here we describe the protective effects of acute and chronic keto acids supplementation on nitrogen metabolism and physical performance in male rats submitted to a resistance training protocol. This study investigated the protective effect of supplementation keto analogues against acute nitrogen compounds and physical performance in rats submitted to exercise.