Coronavirus (COVID-19 ou SARS-COV-2): clinical trials assessment

Clinical tests (TRL5 to TRL9) of the new corona virus have been mapped in order to obtain the current state of the art. The international base of the World Health Organization was mapped and complemented with national bases. After screening, 661 documents remained and were analyzed. There are studie...

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Detalles Bibliográficos
Autores: Quintella, Cristina M., Quintella, Heitor da Mata, Palma, Giovanni Batista, Silva, Sávio Carlos Rodrigues da, Silva, Gustavo Henrique Ramos
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Brasil
Institución:Universidade Federal da Bahia (UFBA)
Repositorio:Cadernos de Prospecção (Online)
Idioma:portugués
OAI Identifier:oai:ojs.periodicos.ufba.br:article/36175
Acceso en línea:https://periodicos.ufba.br/index.php/nit/article/view/36175
Access Level:acceso abierto
Palabra clave:Terapias
Avaliação Tecnológica
Níveis de Maturidade Tecnológica
TRL.
Pandemics
Therapies
Technology Assessment
Technology Readiness Levels
Descripción
Sumario:Clinical tests (TRL5 to TRL9) of the new corona virus have been mapped in order to obtain the current state of the art. The international base of the World Health Organization was mapped and complemented with national bases. After screening, 661 documents remained and were analyzed. There are studies in 25 countries, although they are concentrated in China. Companies finance less than 6% of studies. The vast majority of studies are in Phase Zero (preclinical), only 2% are already in progress and none has results yet. Their primary goals are therapeutics; however, a large majority are dedicated to Chinese medicine and only 245 are focusing on antiviral, immunotherapy and vaccine transnational technologies. There is a wide range of active compounds, mainly referring to hydroxychloroquine/chloroquine (31) and stem cells (22). The age groups of the patients focus especially on adolescents and adults and leave long-lived patients uncovered.