Dental mineralization and salivary activity are reduced in offspring of spontaneously hypertensive rats (SHR)

Several pathologies have been diagnosed in children of hypertensive mothers; however, some studies that evaluated the alterations in their oral health are not conclusive. This study analyzed the salivary gland activity and dental mineralization of offsprings of spontaneously hypertensive rats (SHR)....

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Detalles Bibliográficos
Autores: Elias, Gracieli Prado, Santos, Otoniel Antonio Macedo dos, Sassaki, Kikue Takebayashi, Delbem, Alberto Carlos Botazzo, Antoniali, Cristina
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Brasil
Institución:Universidade de São Paulo (USP)
Repositorio:Journal of applied oral science (Online)
Idioma:inglés
OAI Identifier:oai:revistas.usp.br:article/3381
Acceso en línea:https://www.revistas.usp.br/jaos/article/view/3381
Access Level:acceso abierto
Palabra clave:Hipertensão
Rato espontaneamente hipertenso (SHR)
Saliva
Mineralização de dente
Hypertension
Spontaneously hypertensive rat (SHR)
Tooth mineralization
Descripción
Sumario:Several pathologies have been diagnosed in children of hypertensive mothers; however, some studies that evaluated the alterations in their oral health are not conclusive. This study analyzed the salivary gland activity and dental mineralization of offsprings of spontaneously hypertensive rats (SHR). Thirty-day-old SHR males and Wistar rats were studied. The salivary flow was evaluated by injection of pilocarpine, the protein concentration and salivary amylase activity, by the Lowry method and kinetic method at 405 nm, respectively. Enamel and dentin mineralization of the mandibular incisors was quantified with aid of the microhardness meter. The results were analyzed by the ANOVA or Student's t test (p