Dental mineralization and salivary activity are reduced in offspring of spontaneously hypertensive rats (SHR)

Several pathologies have been diagnosed in children of hypertensive mothers; however, some studies that evaluated the alterations in their oral health are not conclusive. This study analyzed the salivary gland activity and dental mineralization of offsprings of spontaneously hypertensive rats (SHR)....

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Bibliographic Details
Authors: Elias, Gracieli Prado, Santos, Otoniel Antonio Macedo dos, Sassaki, Kikue Takebayashi, Delbem, Alberto Carlos Botazzo, Antoniali, Cristina
Format: article
Status:Published version
Publication Date:2006
Country:Brasil
Institution:Universidade de São Paulo (USP)
Repository:Journal of applied oral science (Online)
Language:English
OAI Identifier:oai:revistas.usp.br:article/3381
Online Access:https://www.revistas.usp.br/jaos/article/view/3381
Access Level:Open access
Keyword:Hipertensão
Rato espontaneamente hipertenso (SHR)
Saliva
Mineralização de dente
Hypertension
Spontaneously hypertensive rat (SHR)
Tooth mineralization
Description
Summary:Several pathologies have been diagnosed in children of hypertensive mothers; however, some studies that evaluated the alterations in their oral health are not conclusive. This study analyzed the salivary gland activity and dental mineralization of offsprings of spontaneously hypertensive rats (SHR). Thirty-day-old SHR males and Wistar rats were studied. The salivary flow was evaluated by injection of pilocarpine, the protein concentration and salivary amylase activity, by the Lowry method and kinetic method at 405 nm, respectively. Enamel and dentin mineralization of the mandibular incisors was quantified with aid of the microhardness meter. The results were analyzed by the ANOVA or Student's t test (p